Glycine--tRNA Ligase (GARS-1) (AA 531-739) Antikörper

Produktnummer ABIN5697760

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch in ELISA, WB, IHC, IF und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Glycine--tRNA Ligase (GARS-1) (AA 531-739) Antikörper (ABIN5697760)

Target: Glycine--tRNA Ligase (GARS-1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails

Bindungsspezifität: AA 531-739

Verwendungszweck: GARS1 antibody

Immunogen:

Immunogen sequence: 531-739aa

Immunogen: glycyl-tRNA synthetase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab03347(GARS antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Antigendetails

Target: Glycine--tRNA Ligase (GARS-1)

Andere Bezeichnung: GARS1

Hintergrund:

Synonyms: Glycine--tRNA ligase|Diadenosine tetraphosphate synthetase (Ap4A synthetase)|Glycyl-tRNA synthetase (GlyRS)|Glycyl-tRNA synthetase 1|GARS1|GARS

Background: This gene encodes glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. The encoded enzyme is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 75-80 kDa

Gen-ID: 2617

UniProt: P41250